Researchers add spice to battle neuromuscular disease

The research by scientists at the University of Rochester Medical Center appears in the March 6 issue of the journal Nature Medicine.

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experiments reported in Nature Medicine, mice carrying the human gene that were treated with ASC-J9 experienced a remarkable improvement. Their muscles appeared to work normally, and they lived 40 percent longer than the untreated mice.

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Among the compounds tested is ASC-J9, a synthetic chemical compound that is loosely based on a compound found in curcumin. Significantly, however, ASC-J9 has been chemically modified compared to its natural counterpart to make it much more powerful.



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